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reveal that GHRP-6 alone was associated with a peak growth hormone response around 60 mU/L, while the combination of GHRP-6 with full-length GHRH was reported to raise the peak to roughly 140 mU/L, or 7-fold higher than the highest physiological peaks

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GHRP-6 binds to ghrelin receptors, prompting the hypothalamus and pituitary gland to release growth hormone, which supports metabolic efficiency and promotes fat loss while preserving muscle (2)

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These include the dopamine 1 receptor (D1R), the dopamine 2 receptor (D2R), the melanocortin-3 receptor (MC3R), the serotonin 2C receptor (5-HT 2C ), and possibly the cannabinoid type 1 receptor (CB1)

Exploratory signals in open laparotomy subgroups did not reach significance